10 high-yield NEET PG-style MCQs with detailed explanations, mixing image-based and text-based questions.
1
Neurology
A young man presents to the medical OPD with early-morning low backache and stiffness that improves with exercise, plus persistent red eyes. Chest expansion is <3 cm. The spinal X-ray is shown. What is the most probable diagnosis?
2
Cardiology
A patient presents with chest discomfort and palpitations. The 12-lead ECG is shown. Which drug is used for prophylaxis of this rhythm?
3
Nephrology
A community respiratory illness prevention program is being reviewed. The public-health photograph is shown. All of the following are proven preventive measures EXCEPT?
4
Hematology(INI-CET 2024)
A 28-year-old HIV-positive man with a CD4 count of 40 cells/µL and a history of significant stray cat exposure presents with multiple friable, red, highly vascular papules on his skin that bleed easily with minor trauma. Biopsy of a lesion reveals a lobular proliferation of blood vessels and a dense neutrophilic infiltrate. Warthin-Starry silver stain demonstrates clusters of small bacilli. What is the drug of choice for this condition?
5
Endocrinology
A 4-year-old boy presents to the pediatric clinic with delayed closure of cranial fontanelles and abnormally hypermobile shoulders allowing him to touch them together anteriorly. A chest radiograph reveals absent clavicles. Genetic analysis identifies a heterozygous inactivating mutation. Which of the following transcription factors is most likely defective in this patient?
6
Hepatology(INI-CET 2023)
A 62-year-old man with severe, poorly controlled rheumatoid arthritis is evaluated for fatigue. His hemoglobin is 10.2 g/dL, and his MCV is 78 fL. Iron studies reveal a low serum iron, a low total iron-binding capacity (TIBC), and a markedly elevated serum ferritin. Which of the following molecules is primarily responsible for sequestering iron in his macrophages, limiting its availability for erythropoiesis?
7
Gastroenterology
A 50-year-old patient presents to the clinic with an extensive history of severe arthralgias, profound weight loss, chronic diarrhea, and abdominal pain. Upper endoscopy with small-intestinal biopsy reveals a dense infiltration of periodic acid-Schiff positive macrophages in the lamina propria, confirming a systemic infectious process. Based on established epidemiological patterns, which of the following demographic profiles is most highly associated with this specific disease?
8
Pulmonology
A patient with high fever and altered sensorium has cerebrospinal fluid drawn. The Gram stain photomicrograph is shown. Most appropriate empirical antibiotic?
9
General Medicine(INI-CET 2023)
A poorly controlled diabetic patient presents with severe facial pain and a necrotic black eschar on the hard palate. A rapid biopsy reveals broad, non-septate, ribbon-like hyphae branching at right angles. The resident suggests starting empirical voriconazole. Why is voriconazole an inappropriate choice for this specific patient?
10
Rheumatology
A 65-year-old female presents with new-onset bilateral shoulder and pelvic girdle pain and stiffness, along with swelling in her proximal interphalangeal joints. Her erythrocyte sedimentation rate is markedly elevated. The physician suspects polymyalgia rheumatica but notes the peripheral arthritis could also represent elderly-onset rheumatoid arthritis. Which of the following is the most appropriate next step to differentiate these two conditions?